Main

Fields of interest:

• Structure and dynamics of biomolecules
• NMR spectroscopy
• Theoretical calculations of NMR parameters
• MD simulations

Recent publications:

M. Munzarová and V. Sklenář:
Three-Bond Sugar-Base Couplings in Purine versus Pyrimidine Nucleosides: A DFT Study of Karplus Relationships for 3JC2/4-H1' and 3JC6/8-H1' in DNA,
J. Amer. Chem. Soc., Vol. 124, (2002), pp. 10666-10667.

P. Padrta and V. Sklenář:
Program MULDER - A tool for Extracting Torsion Angles from NMR Data,
J. Biomol. NMR, Vol. 24, (2002), pp. 349-449.

L. Žídek, P. Padrta, J. Chmelík, Jr. and V. Sklenář:
Internal Consistency of NMR Data Obtained in Partially Aligned Biomacromolecules,
J. Magn. Reson., Vol. 162, (2003), pp. 385-395.

M. Munzarová and V. Sklenář:
A DFT Analysis of NMR Scalar Interactions Across the Glycosidic Bond in DNA,
J. Amer. Chem. Soc., Vol. 125, (2003), pp. 3649-3658.

H. Křížová, L. Žídek, M. Stone, M.V. Novotny and V. Sklenář:
Temperature Dependent Backbone Dynamics of Major Urinary Protein-I Complexed with the Pheromone 2-sec-butyl-4,5-dihydrothiazole,
J. Biomol. NMR, Vol. 28, (2004), pp. 369-384:

R. Štefl, H. Wu, S. Ravindranathan, V. Sklenář and J. Feigon:
DNA A-tract bending in three dimensions--solving the dA4T4 versus dT4A4 conundrum,
Proc. Nat. Acad. Sci., Vol. 101, (2004), pp. 1171-1176.

R. Fiala, M. Munzarová and V. Sklenář:
Experiments for Correlating Quaternary Carbons in RNA Bases,
J. Biomol. NMR, Vol. 29, (2004), pp. 477-490.

R. Marek and V. Sklenář:
NMR Studies of Purines,
Ann. Rep. NMR Spect., Vol. 54, (2005), pp. 201-242.

P. Macek, P. Novák, H. Křížová, L. Žídek and V. Sklenář:
Molecular Dynamics Study of Major Urinary Protein - Pheromone Interactions: A structural Model for Ligand-Induced Flexibility Increase,
FEBS Letters, Vol. 580, (2006), pp. 682-684:

M. Hennig, M.L. Munzarová, W. Bermel, L.G. Scott, V. Sklenář and J.R. Williamson:
Measurement of Long-Range 1H-19F Scalar Coupling Constants and Their Glycosidic Torsion Dependence in 5-Fluoropyrimidine-Substituted RNA,
J. Amer. Chem. Soc., Vol. 128, (2006), pp. 5851-5858.