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Fields of interest:

• Biomineralisation and Biomimetics of magnetotactic bacteria
• Pathogenecity of /Neisseria meningitidis/ and Enzymology Methionine Sulphoxide Ruductases
• Enzyme Mimics - hydrolytic catalytic antibodies and hydrolytic enzymes

Recent publications:

V. Khare, S. Sonkari and C. Ruby:
Surface Coating of Iron Oxide on Sand: Key Aspects. (Abstract accepted for an invited review article as an edited collection on Surface Coatings, manuscript in preparation),
Nova Science Publishers, New York, 2008.

S. Boshi-Muller, S. Sonkaria, F. Neiers and G. Branlant:
Methionine sulfoxide reductases from class B : Characterization of the amino acids from /Neisseria meningitidis /methionine sulfoxide reductase B involved in the chemical catalysis and substrate specificity of the reductase step.specificity,
J. Biol. Chem., Vol. 282, (2007), pp. 32397-32405.

S. Sonkaria, G. Boucher, J. Florez-Alvarez, B. Said, S. Hussain, S. Gul, E.W. Thomas, E. Ostler, M. Resmini, G. Gallacher and K. Brocklehurst:
Evidence for 'lock and key' character in an anti-phosphate hydrolytic antibodycatalytic site augmented by non- reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody and two hydrolytic enzymes,
Biochem. J., Vol. 381, (2004), pp. 125-130.

J. D. Reid, S. Hussain, T.S. Bailey, S. Gul, S. Sonkaria, S.K. Sreedharan, E.W. Thomas, M. Resmini and K. Brocklehurst:
Isomerization of the actinidin molecule prior to enzyme-substrate complex formation: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation,
Biochem. J., Vol. 378, (2004), pp. 699-703.

S. Gul, S. Sonkaria, S. Pinitglang, J. Florez-Alvarez, S. Hussain, E.W. Thomas, E.L. Ostler, M. Resmini, S. Carter, C.M. Topham, G. Gallacher and K. Brocklehurst:
Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving group determinant: unequivocal evidence for the 'flexibility' hypothesis,
Biochem. J., Vol. 376, (2003), pp. 813-821.

C.M. Topham, S. Gul, M. Resmini, S. Carter, S. Sonkaria, G. Gallacher and K. Brocklehurst:
The Kinetic Basis of a General Kinetic Approach for the Investigation of Active-Site Content of Enzymes and Catalytic Antibodies: First-Order Behaviour under Single-Turnover and Cycling Conditions,
J. Theor. Biol., Vol. 204, (2000), pp. 239-256.

M. Resmini, S. Gul, S. Carter, S. Sonkaria, C.M. Topham, G. Gallacher and K. Brocklehurst:
A General Kinetic Approach to the Investigation of Active-Site Availability in Macromolecular Catalysts,
Biochem. J., Vol. 346, (2000), pp. 117-125.

S. Sonkaria, S. Gul, M. Resmini, G. Gallacher and K. Brocklehurst:
Evaluation of a Kinetic Approach to the Determination of Catalytic Site Content in Enzymes and Enzyme Like Catalysts.
Biochem. Soc. Trans., Vol. 27, (1999), p. 22.

M.Resmini, S. Gul, S. Carter, S. Sonkaria, G. Gallacher and K. Brocklehurst:
Determination of the Catalytic Site Content of a Catalytic Antibody Preparation.
Biochem. Soc. Trans., Vol. 26, (1998), pp. 170.