Main

Fields of interest:

• Vision research
• Signal transduction
• Retina diseases

Recent publications:

R.E. Stenkamp, D.C. Teller, K. Palczewski:
Rhodopsin: A structural primer for G-protein coupled receptors,
Archiv der Pharmazie, Vol. 338, (2005), pp. 209-216.

M. Golczak, Y. Imanishi, V. Kuksa, T. Maeda, R. Kubota, K. Palczewski:
Lecithin retinol acyl transferase (LRAT) is responsible for amidation of retinylamine, a potent inhibitor of the visual cycle,
J. Biol. Chem., Vol. 280, (2005), pp. 42263-42272.

S.E. Mansoor, K. Palczewski, D.L. Farrens:
Rhodopsin self-associates in asolectin liposomes,
Proc. Natl. Acad. Sci. USA, Vol. 103, (2006), pp. 3060-3065.

K.T. Sapra, P.S.-H. Park, S. Filipek, A. Engel, D.J. Muller, K. Palczewski:
Detecting molecular interactions that stabilize native bovine rhodopsin,
J. Mol. Biol., Vol. 358, (2006), pp. 255-269.

A. Maeda, T. Maeda, Y. Imanishi, M. Golczak, A.R. Moise, K. Palczewski:
Aberrant metabolites in mouse models of congenital blinding diseases: Formation and storage of retinyl esters,
Biochemistry, Vol. 45, (2006), pp. 4210-4219.

D. Fotiadis, B. Jastrzebska, A. Philippsen, D.J. Müller, K. Palczewski, A. Engel:
Structure of the Rhodopsin Dimer: A Working Model for G-Protein Coupled Receptors,
Current Op. Structural Biol., Vol. 16, (2006), pp. 252-259.

B. Jastrzebska, D. Fotiadis, G.-F. Jang, R.E. Stenkamp, A. Engel, K. Palczewski:
Functional and structural characterization of rhodopsin oligomers,
J. Biol. Chem., Vol. 281, (2006), pp. 11917-11922.

R. Stephen, K. Palczewski, M.C. Sousa:
The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP–linked Cone Dystrophies,
J. Mol. Biol., Vol. 359, (2006), pp. 266-275.

S.E. Haire, J. Pang, S.L. Boye, I. Sokal, C.M. Craft, K. Palczewski, W.W. Hauswirth,
S.L. Semple-Rowland:
AAV-GC1 restores function to cone photoreceptors in postnatal GC1 KO mouse retina,
Invest Ophthalmol Vis Sci, (in press).

K. Palczewski:
G Protein-Coupled Receptor Rhodopsin,
Annual Review of Biochemistry, Vol. 75, (2006) (in press).