Main

Fields of interest:

• Biophysical theory and modeling:
• cellular biophysics (modeling and computer simulations of the self assembly of cells into tissues in developmental biology and tissue engineering, cell motility in three-dimensional environments);
• molecular biophysics (kinetic models of active transport, the impact of membrane potential fluctuations on active transport, the effects of electrolyte cosolutes on protein structure and activity)

Recent publications:

A.R. Small, A. Neagu, F. Amyot, D. Sackett, V. Chernomordik, A. Gandjbakhche:
Spatial distribution of VEGF isoforms and chemotactic signals in the
vicinity of a tumor,
J. Theor. Biol., Vol. 252, (2008), pp. 593-607.

I.O. Doaga, T. Savopol, M. Neagu, A. Neagu, E. Kovács:
The Kinetics of Cell Adhesion to Solid Scaffolds: An Experimental and Theoretical Approach,
J. Biol. Phys., Vol. 34, (2008), pp. 495-509.

C. Norotte, F. Marga, A. Neagu, I. Kosztin, G. Forgacs:
Experimental evaluation of apparent tissue surface tension based on the exact solution of the Laplace equation
Europhysics Letters, Vol 81, (2008), p. 46003.

K. Jakab, C. Norotte, B. Damon, F. Marga, A. Neagu, C.L. Besch-Williford, A. Kachurin, K.H. Church, H. Park, V.V. Mironov, R.R. Markwald, G. Vunjak-Novakovic, G. Forgacs:
Tissue Engineering by Self-Assembly of Cells Printed into Topologically Defined Structures
Tissue Engineering: Part A, Vol 14, (2007), pp. 413-421.

F. Marga, A. Neagu, I. Kosztin, G. Forgacs:
Developmental Biology and Tissue Engineering,
Birth Defects Research (Part C), Vol. 81, (2007), pp. 320-328.

E. Flenner, F. Marga, A. Neagu, I. Kosztin, G. Forgacs:
Relating Biophysical Properties Across Scales, 
Curr. Top. Dev. Biol., Vol. 81, (2007), pp. 461-483.

A. Neagu, I. Kosztin, K. Jakab, B. Barz, M. Neagu, R. Jamison and G. Forgacs:
Computational modeling of tissue self-assembly,
Modern Phys. Lett. B, Vol. 20, (2006), pp. 1217-1231.

K. Jakab, B. Damon, A. Neagu, A. Kachurin and G. Forgacs:
Three-dimensional tissue constructs built by bioprinting,
Biorheology, Vol. 43, (2006), pp. 509-513.

A. Neagu, K. Jakab, R. Jamison and G. Forgacs:
Role of physical mechanisms in biological self-organization,
Phys. Rev. Lett., Vol. 95, (2005), pp. 178104-1-4.

K. Jakab, A. Neagu, V. Mironov, R.P. Markwald and G. Forgacs:
Engineering biological structures of prescribed shape using self-assembling multicellular systems,
Proc. Natl. Acad. Sci. USA, Vol. 101, (2004), 2864-2869.