Main

Fields of interest:
Structural aspects of bioactive compounds and their mode of action

Recent publications:
S.B.Vogensen, K.Stromgaard, H.Shindou, S. Jaracz, M.Suehiro, S. Ishii, T. Shimizu, Takao, K.Nakanishi
Preparation of 7-Substituted Ginkgolide Derivatives: Potent Platelet Activating Factor (PAF) Receptor Antagonists
J. Med. Chem. 46, 601-608 (2003)

N. Nesnas, R. R. Rando, K. Nakanishi
Synthesis of Biotinylated Retinoids for Cross-Linking and Isolation of Retinol Binding Proteins
Tetrahedron, 58, 6577-6584 (2002)

Y. Fujimoto, N. Fishkin, G. Pescitelli, J. Decatur, N. Berova, K. Nakanishi
Solution and Biologically Relevant Conformations of Enantiomeric 11-cis-Locked Cyclopropyl Retinals
J. Am. Chem. Soc., 124, 25, 7294-7302 (2002)

C.A. Parish, H. Jiang, Y. Tokiwa, N. Berova, K. Nakanishi, D. McCabe, W. Zuckerman, M.M. Xia, J.E. Gabay
Broad-Spectrum Antimicrobial Activity of Hemoglobin
Bioorganic & Medicinal Chem., 9, 377-­382 (2001)

A. Kawamura, L.M. Abrell, F. Maggiali, N. Berova, K. Nakanishi, J. Labutti, G.T.J. Haupert, J.M. Hamlyn
Conformational Flexibility of Ouabain and Its Biological Implication: Observations with Ouabain 1,5,19- and 1,11,19-Phosphates
Biochemistry, 40 (2001)

T. Kurtan, N. Nesnas, Y.-Q. Li, X. Huang, K. Nakanishi, N. Berova
Chiral Recognition by CD-Sensitive Dimeric Zinc Porphyrin Host. 1. Chiroptical Protocol for Absolute Configurational Assignments of Monoalcohols and Primary Monoamines
J. Am. Chem. Soc., 123, 25, 5962-­5973 (2001)

T. Kurtan, N. Nesnas, F.E. Koehn, Y.-Q. Li, K. Nakanishi, N. Berova
Chiral Recognition by CD-Sensitive Dimeric Zinc Porphyrin Host. 2. Structural Studies of Host-Guest Complexes with Chiral Alcohol and Monoamine Conjugates
J. Am. Chem. Soc., 123, 25, 5974-­5982 (2001)

S. Ben-Shabat, C.A. Parish, M. Hashimoto, J. Liu, K. Nakanishi, J.R. Sparrow
Fluorescent Pigments of the Retinal Pigment Epithelium and Age-Related Macular Degeneration
Bioorganic & Medicinal Chem., 11, 1533-­1540 (2001)

S. Huang, K. Nakanishi, N. Berova
Porphyrins and Metalloporphyrins: Versatile Circular Dichroic Reporter Groups for Structural Studies
Chirality, 12, 237-­255 (2000)

B.Borhan, M.L.Souto, H.Imai, Y.Shichida, K.Nakanishi
Movement of Retinal Along the Visual Transduction Path
Science, 288, 2209-2212 (2000)