Main

Fields of interest:

• Structural and mechanistic studies of platinum anticancer drugs .
• Synthesis of dimetallic complexes as models for non-heme iron enzymes and metallohydrolases.
• Mechanistic studies of methane monooxygenase .

Recent publications:

E.C. Carson, S.J. Lippard:

Synthesis and Oxidation of Carboxylate-Bridged Diiron(II) Complexes with Substrates Tethered to Primary Alkyl Amine Ligands.
J. Inorg. Biochem., Vol. 100, (2006), pp. 1109-1117 .

C.J. Chang, S.J. Lippard:
Zinc Metalloneurochemistry: Physiology, Pathology, Probes.
Met. Ions Life Sci., Vol. 1,(2006), pp. 321--370 .

T.C. Harrop, D. Song, S.J. Lippard:
Interaction of Nitric Oxide with Tetrathiolato Iron(II) Complexes: Relevance to the Reaction Pathways of Iron Nitrosyls in Sulfur-Rich Biological Coordination Environments.
J. Am. Chem. Soc., Vol. 128, (2006), pp. 3528-3529.

E.M. Nolan, M.E. Racine, S.J. Lippard:
Selective Hg(II) Detection in Aqueous Solution with Thiol Derivatized Fluoresceins.
Inorg. Chem., Vol. 45, (2006), pp. 2742-2749 .

L.J. Giblin, C.J. Chang, A.F. Bentley, C. Frederickson, S.J. Lippard and C.J. Frederickson:
Zinc-Secreting Paneth Cells Studied by ZP Fluorescence.
J. Histochem. Cytochem., Vol. 54,(2006), pp. 311-316 .

Y. Jung and S.J. Lippard:
RNA Polymerase II Blockage by Cisplatin-Damaged DNA: Stability and Polyubiquitylation of Stalled Polymerase.
J. Biol. Chem., Vol. 281, (2006), pp. 1361-1370.

C.R. Goldsmith, J. Jaworski, M. Sheng, S.J. Lippard:
Selective Labeling of Extracellular Proteins Containing Polyhistidine Sequences by a Fluorescein-Nitrilotriacetic Acid Conjugate.
J. Am. Chem. Soc., Vol. 128, (2006), pp. 418-419 .

E.C. Carson and S.J. Lippard:
Dioxygen-Initiated Oxidation of Heteroatomic Substrates Incorporated into Ancillary Pyridine Ligands of Carboxylate-Rich Diiron(II) Complexes.
Inorg. Chem., Vol. 45, (2006), pp. 837-848 .

E.C. Carson and S.J. Lippard:
Synthesis, Characterization, and Preliminary Oxygenation Studies of Benzyl- and Ethyl-Substituted Pyridine Ligands of Carboxylate-Rich Diiron(II) Complexes.
Inorg. Chem., Vol. 45, (2006), pp. 828-836 .

C.R. Goldsmith and S.J. Lippard:
6-Methylpyridyl for Pyridyl Substitution Tunes the Properties of Fluorescent Zinc Sensors of the Zinpyr Family.
Inorg. Chem., Vol. 45, (2006), pp. 555--561 .