Main

Fields of interest:

• macromolecular NMR
• structural biology
• biophysics
• metabolomics

Recent publications:

  
T.W-M. Fan, P. Lorkiewicz,  K. Sellers, H.N.B. Moseley, R.M. Higashi, A.N. Lane:
Stable isotope-resolved metabolomics and applications to drug development,
Pharmacology & Therapeutics.,  Vol. 133, (2012), pp. 366-391 

A. Le, A.N. Lane, M. Hamaker, S. Bose, J. Barbi, T. Tsukamoto, C.J. Rojas, B.S. Slusher, H. Zhang, L.J. Zimmerman, D.C. Liebler, R.J.C. Slebos, P.K. Lorkiewicz, R.M. Higashi, T.W.M. Fan, C.V. Dang:
Myc induction of hypoxic glutamine metabolism and a glucose- independent TCA cycle in human B lymphocytes         
Cell Metabolism., Vol. 15, (2012), pp. 110-121            

H.N.B. Moseley, A.N. Lane, A.C. Belshoff, R.M. Higashi, W.W-M. Fan:
Non-Steady State Modeling of UDP-GlcNAc Biosynthesis is  Enabled by Stable Isotope, Resolved Metabolomics (SIRM),
BMC Biology, Vol. 9, (2011), pp.37

M.M. Dailey, M.C. Miller, P.J. Bates, A.N. Lane, J.O. Trent:
Resolution and characterization of the structural polymorphism of a single quadruplex-formingsequence,
Nucl. Acids Res., Vol. 38, (2010), pp.4877-4888 

A.V. Chernatynskaya, L. Deleeuw, J.O. Trent, T. Brown, A.N. Lane:
Structural analysis of the DNA target site and its interaction with Mbp1,
Org.Biomolec. Chem., Vol. 7, (2009), pp.4981-4991

A.N. Lane, J.B. Chaires, R.D. Gray, J.O. Trent:
Stability and kinetics of G-quartet structures
Nucl. Acids Res., Vol.36, (2008), pp.5482-5515