Main

Fields of interest:

• Translation
• Telomerase
• Ribonucleoprtein compexes

Recent publications:

P.V. Sergiev, A.A. Bogdanov and O.A. Dontsova:
Ribosomal RNA guanine-(N2)-methyltransferases and their targets,
Nucleic Acids Res., Vol. 35, (2007), pp. 2295-2301.

P.V. Sergiev, M.V. Serebryakova, A.A. Bogdanov and O.A. Dontsova:
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel,
J. Mol. Biol., Vol. 375, (2007), pp.291-300.

D.V. Lesnyak, J. Osipiuk, T. Skarina, P.V. Sergiev, A.A. Bogdanov, A. Edwards, A. Savchenko, A. Joachimiak and O.A. Dontsova:
Methyltransferase that modifies guanine 966 of the 16S rRNA: functional identification and tertiary structure,
J. Biol. Chem., Vol. 282, (2007), pp.5880-5887.

Y.S. Sharanov, M.I. Zvereva and O.A. Dontsova:
Saccharomyces cerevisiae telomerase subunit Est3p binds DNA and RNA and stimulates unwinding of RNA/DNA heteroduplexes,
FEBS Lett., Vol. 580, (2006), pp. 4683-4690.

D.V. Lesnyak, P.V. Sergiev, A.A. Bogdanov and O.A. Dontsova:
Identification of Escherichia coli m2G methyltransferases:
I. The ycbY gene encodes a methyltransferase specific for G2445 of the 23S rRNA,
J. Mol. Biol., Vol. 364, (2006), pp. 20-25.

P.V. Sergiev, D.V. Lesnyak, A.A. Bogdanov and O.A. Dontsova:
Identification of Escherichia coli m2G methyltransferases:
II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23S rRNA,
J. Mol. Biol., Vol. 364, (2006), pp. 26-31.

A. Kubarenko, P. Sergiev, W. Wintermeyer, O. Dontsova and M.V. Rodnina:
Involvement of Helix 34 of 16 S rRNA in Decoding and Translocation on the Ribosome,
J. Biol. Chem., Vol. 281, (2006), pp. 35235-35244.

O.V. Shpanchenko, M.I. Zvereva, P.V. Ivanov, E.Yu. Bugaeva, A.S. Rozov, A.A. Bogdanov, M. Kalkum, L. Isaksson, K.H. Nierhaus and O.A. Dontsova:
Stepping tmRNA through the ribosome,
J. Biol. Chem., Vol. 280, (2005), pp. 18368-18374.

P.V. Sergiev, D.V. Lesnyak, D.E. Burakovsky, S.V. Kiparisov, A.A. Leonov, A.A. Bogdanov, R. Brimacombe and O.A. Dontsova:
Alteration in Location of a Conserved GTPase-associated Center of the Ribosome Induced by Mutagenesis Influences the Structure of Peptidyltransferase Center and Activity of Elongation Factor G.,
J. Biol. Chem., Vol. 280, (2005), pp. 31882-31889.

P.V. Sergiev, S.V. Kiparisov, D.E. Burakovsky, D.V. Lesnyak, A.A. Leonov, A.A. Bogdanov and O.A. Dontsova:
The Conserved A-site Finger of the 23S rRNA: Just One of the Intersubunit Bridges or a Part of the Allosteric Communication Pathway?
J. Mol. Biol., Vol. 353, (2005), pp. 116-123.