Main

Fields of interest:

• Synthesis of mimics of antibodies or of biological receptor sites
• Artificial enzymes, reactions in water, and nanochemistry

Recent publications:
R. Breslow, ed.:
Artificial Enzymes,
Wiley-VCH, Weinheim, Germany, 2005.

M.R. Biscoe and R. Breslow:
Oxaziridinium Salts as Hydrophobic Epoxidation Reagents: Remarkable Hydrophobically-Directed Selectivity in Olefin Epoxidation,
J. Am .Chem. Soc. 127, 10812-10813 (2005).

J.J. Chruma, L. Liu, W. Zhou and R. Breslow:
Hydrophobic and electronic factors in the design of dialkylglycine decarboxylase mimics,
Bioorg. Med. Chem. 13, 5873-5883 (2005).

Z. Fang and R. Breslow:
A Thiolate Ligand on a Cytochrome P-450 Mimic Permits the Use of Simple Environmentally Benign Oxidants for Biomimetic Steroid Hydroxylation in Water,
Biorg. Med. Chem. Lett. 2005, 15, 5463-5466.

C. Uyeda, M. Biscoe, P. LePlae and R. Breslow:
Hydrophobically directed selective reduction of ketones using amine boranes,
Tetrahedron Lett. 2005, 47, 127-130.

X. Guo, R. Breslow et al.:
Covalently Bridging Gaps in Single-Walled Carbon Nanotubes with Conducting Molecules,
Science 2006, 311, 356-359.

I.W. Tam, J. Yan, and R. Breslow:
An 11 nm Molecular Wire that Switches Electrochemically between an Insulating and a Fully Conjugated Conducting State,
Org. Lett. 2006, 8, 183-185.

Z. Fang and R. Breslow:
Metal Coordination-Directed Hydroxylation of Steroids with a Novel Artificial P-450 Catalyst,
Org. Lett. 2006, 8, 251-254.

R. Breslow and M. Levine:
Partial transfer of enantioselective chiralities from a-methylated amino acids, known to be of meteoritic origin, into normal amino acids,
Tetrahedron Lett. 2006, 1809-1812.