Main

Fields of interest:

• Cell Biology and Functional Morphology of Cell and Tissues: Endothelial cells, Smooth Muscle Cells; Neurons and as well as Glial and Macrophages Cells
• Specific characteristic changes of cell morphology in different functional states; particularly atherogenesis, vascular remodeling, hypertension, ischemia/reperfusion, tumor angiogenesis, signal transduction and mitochondria DNA deletion and/or overproliferation during cancer growth, metastases and Alzheimer’s diseases
• Regulation mechanisms of specific nitric oxide synthase (NOS) expression in endothelial and smooth muscle cells and macrophages in vivo and in vitro

Recent publications:

V. Bragin, M. Chemodanova, I. Bragin, N. Dzhafarova, I. Mescher, P. Chernyavskyy,   M.E. Obrenovich, H.H. Palacios, G. Aliev:
 A 60-month follow-up of a naturalistic study of integrative treatment for real-life geriatric patients with depression, dementia and multiple chronic illnesses,
Open Journal of Psychiatry,  April 30, 2012,  (in press)

G. Aliev:
“The Role of Oxidative Stress, Mitochondria Failure, and Cellular Hypoperfusion in the Context of Alzheimer Disease: Past, Present and Future”,
Monograph Book: Nova Science Publishers, Inc., New York, (2012)  
ISBN: 978-1-61942-878-2. (in press)

S.I. Magalov, N.F. Hasanov, N.X. Azizova, A.N. Novruzov, Z.B. Mustafayev, S.A. Kazimov, S.S. Sultanov, E.N. Hasanov, G. Aliev:
The Prevalence of Epilepsy in the Nakhichevan Autonomous Republic of Azerbaijan,
CNS Neurol Disord Drug Targets, Vol.11(8), (2012),  ISSN: 1871-5273

X. Zhu, R.J. Castellani, P.I. Moreira, G. Aliev, J.C. Shenk, S.L. Siedlak, P.L.R. Harris, H. Fujioka, L.M. Sayre, P.A. Szweda, L.I. Szweda, M.A. Smith, G. Perry:
Hydroxynonenal-generated crosslinking Fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover,
Free Radic Biol Medicine, Vol.52(3), (2012), pp.699-704.

M.E. Obrenovich, K. Gasiorowski, H.H. Palacios, D. Gokhman, V.B. Shadlinski, V. Bragin,  J. Leszek, G. Aliev:
Selective loss of GRK2 regulation and its consequences: cerebrovascular complications and Alzheimer disease,
Polish Journal of Geriatric Psychiatry (Psychogeriatria Polska), Vol.8(3-4), (2011), pp.81-98.

G. Aliev, Y. Li, H. Palacios, M.E. Obrenovich: 
Oxidative Stress Induced Mitochondrial DNA Deletion as a Hallmark for the Drug Development in the Context of  the Cerebrovascular Diseases,
Recent Patents on Cardiovascular Drug Discovery, Vol.6, (2011), pp.222-241.

G. Aliev, H.H. Palacios, B.Y. Bhushan, K. Gasiorowski, D. Gokhman, V.B. Shadlinski,  V. Bragin, J. Leszek:
Oxidative Stress Induced Mitochondrial DNA Overproliferation and Deletion, Cellular Hypoperfusion and Brain Hypometabolism In the Context of Cerebrovascular and Alzheimer Disease: Offer  New and Successful Targets for the Drug Delivering and Treatment,
Polish Journal of Geriatric Psychiatry (Psychogeriatria Polska), Vol.8(1), (2011), pp.23-30.

J. Horecký, A. Gvozdjákova, J. Kucharská, M.E. Obrenovich, B.B. Yendluri, H.H. Palacios, O. Vancová, G. Aliev:
Effects of Coenzyme Q and Creatine Supplementation on Brain Energy Metabolism in Rats Exposed to Chronic Cerebral Hypoperfusion,
Curr Alzheimer Res., Vol.8(8), (2011), pp.868-875.

G. Aliev,H. Palacios, B. Betts, M.E. Obrenovich, K. Gasiorowski, D. Gokhman, J. Leszek, V. Bragin: 
Mitochondrion Selective Antioxidants as Drug Treatments for Alzheimer Disease,
In: Vascular Dementia, Editor: Sarah R. Jacobsen,
ISBN: 978-1-61122-313-2, 2011. Nova Science Publishers, Inc. (2011), Chapter IV, pp. 105-128.

G. Aliev,H. Palacios, D. Gokhman, K. Gasiorowski, V. Bragin, J. Leszek, M.E. Obrenovich:
GRK2 Overexpression is a Primary Hallmark of Vascular Hypoperfusion and Mitochondrial Lesions During Early Alzheimer Disease: New Target for Drug Treatment?
In: Vascular Dementia, Editor: Sarah R. Jacobsen,
ISBN: 978-1-61122-313-2, 2011. Nova Science Publishers, Inc. (2011), Chapter III, pp. 79-104.