Main

Fields of interest:

Neurodegeneration

stroke

brain trauma

brain tumours

Recent publications:

Nishimura A.L., Župunski V., Troakes C.,Fratta P, Kathe C., Howell M., Gallo J.-M., Hortobágyi T., Shaw C.E., Rogelj B.:
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.
Brain. 2010;133:1763-1771

Kirvell S.L., Elliott M.S., Kalaria R.N., Hortobágyi T., Ballard C.G., Francis P.T.:
Vesicular glutamate transporter and cognition in stroke: a case-control autopsy study in stroke.
Neurology. 2010;75:1803180-9

Vance C., Rogelj B., Hortobágyi T., De Vos K.J., Nishimura A.L., Sreedharan J., Hu X., Smith B., Ruddy D., Wright P., GaneslingamJ., Tripathi V., Al-Saraj S., Al-Chalabi A., Leigh P.N., Blair I.P., Nicholson G., de Belleroche J., Gallo J-M., Miller C.C., Shaw C.E.:
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6.
Science. 2009;323:1208-1211.

Malik B, Currais A, Andres A, Towlson C, Pitsi D, Nunes A, Niblock M, Cooper J, Hortobágyi T., Soriano S.:
Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the presenilin-1 Alzheimer’s disease brain.
Cell Cycle.2008;7:637-646.

Hortobágyi T.,Wise S., Hunt N., Cary N., Djurovic V., Fegan-Earl A., Shorrock K., Rouse D, Al-Sarraj S.:
Traumatic axonal injury in the brain can be detected using b-APP immunohistochemistry in a minimum of 35 minutes after head injury to human adults.
Neuropathology and Applied Neurobiology. 2007;33:226-237.